SINGAPORE, Nov 4 (Bernama-GLOBE NEWSWIRE) — Tessa Therapeutics Ltd. (Tessa), a clinical-stage cell therapy company developing next-generation cancer treatments for hematological malignancies and solid tumors, today announced that three abstracts reporting data from clinical trials investigating the company’s autologous CD30.CAR-T therapy (TT11) and allogeneic CD30.CAR EBVST therapy (TT11X) have been accepted for presentation at the 64th American Society of Hematology Annual Meeting (ASH 2022) taking place December 10-13, 2022, at the Ernest N. Morial Convention Center in New Orleans.
TT11, Tessa’s lead clinical asset, is an autologous CD30.CAR-T therapy currently being investigated as a potential treatment for relapsed or refractory classical Hodgkin lymphoma (r/r cHL) as both a monotherapy (Phase 2 CHARIOT) and combination therapy (Phase 1b). Two abstracts involving updated data from the CHARIOT clinical trial will be presented at ASH 2022, including an oral podium presentation demonstrating that circulating tumor DNA (ctDNA) analysis with Foresight Diagnostics PhasED-Seq technology provides a viable biomarker to monitor responses, rapidly stratify risk, and predict outcomes of r/r cHL patients treated with TT11.