Adagene Announces FDA Clearance To Proceed With Phase 1b/2 Trial Of Anti-CTLA-4 ADG126 Safebody® In Combination Therapy With Anti-PD-1 Antibody Pembrolizumab

– ADG126-P001 trial being initiated at multiple sites in U.S. and Asia Pacific –

– First SAFEbody candidate to advance into combination clinical trial, building on strong single-agent clinical profile –

SAN DIEGO and SUZHOU, China, March 17 (Bernama-GLOBE NEWSWIRE) — Adagene Inc. (“Adagene”) (Nasdaq: ADAG), a company transforming the discovery and development of novel antibody-based therapies, today announced FDA clearance to proceed with a Phase 1b/2 clinical trial of its anti-CTLA-4 monoclonal antibody (mAb), ADG126, in combination with the anti-PD-1 antibody pembrolizumab. The global trial (ADG126-P001 / KEYNOTE-C98) will evaluate patients with advanced/metastatic solid tumors at multiple sites in the U.S. and Asia Pacific (APAC).

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